Return to search

Testování nových elektrodových uspořádání pro monitorování elektrochemicky oxidovatelných biologicky aktivních organických látek / Testing of new electrode arrangements for monitoring of electrochemically oxidisable biologically active organic compounds

Submitted Ph.D. Thesis is focused on the electrochemical characterization and testing of recently developed working electrodes made from pure gold or graphitic carbon particles and electrochemical arrangements. These electrodes are suitable for large screening measurements of various organic compounds. The development of new sensitive voltammetric methods for determination of oxidisable biologically active organic compounds is another aim of this work. To verify its applicability, the array of carbon composite film electrodes integrated in measuring cell system was selected for the development of voltammetric methods for determination of homovanillic acid, vanillylmandelic acid, and indoxyl sulphate. These analytes, which belong to the group of biomarkers of human diseases, were selected for increasing interest in their determination in medical laboratories. Moreover, determination of indoxyl sulphate was coupled to its solid phase extraction from human urine prior to voltammetric determination. Obtained results were compared with measurements of standards with well-established carbon paste electrode. Sputtered (physical vapour deposition method) gold nanostructured film electrodes on treated PTFE substrates and gold nanostructured film electrodes modified with various functional groups on the...

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:354366
Date January 2017
CreatorsLibánský, Milan
ContributorsZima, Jiří, Navrátil, Tomáš, Šelešovská, Renáta
Source SetsCzech ETDs
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/doctoralThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

Page generated in 0.0017 seconds