Many experiments are being conducted to find compounds that offer
radioprotection against radiation damage and that are also non-toxic. It is hopeful
that in the future, research for this technology will benefit patients undergoing
cancer treatment by reducing radiation damage to normal cells and therefore
reducing short and long term side effects experienced from treatments.
Hamster cells were irradiated at doses of 60 and 120 rad, with and without
Sphingosine-1-Phosphate mixed in with their growth medium. Post irradiation, it
was observed that the S1P molecule seemed to have a radioprotective effect by
decreasing the amount of cell death compared to the amount of cell death that
occurred with the absence of the molecule. The results of this experiment will sent
to Dr. Jon Tilly at Massachusetts General Hospital. Dr. Tilly is currently
researching S1P as a possible radioprotector. / Graduation date: 2003
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/32400 |
| Date | 21 August 2002 |
| Creators | Villamar, Glenda |
| Contributors | Higley, Kathryn H. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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