Indiana University-Purdue University Indianapolis (IUPUI) / In an effort to advance the methodology in analyzing RNAPII protein-protein interaction network and to determine the role of the CTD in controlling RNAPII transcription, we devised a method to specifically isolate the CTD-associated and CTD-less RNAPII to identify the proteins that interact with both the CTD and the globular core of RNAPII using novel purification scheme coupled to quantitative proteomics.
Identifer | oai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/6179 |
Date | 12 1900 |
Creators | Alakhras, Nada S. |
Contributors | Mosley, Amber L., Goebl, Mark G., Hurley, Thomas D., 1961- |
Source Sets | Indiana University-Purdue University Indianapolis |
Language | en_US |
Detected Language | English |
Type | Thesis |
Page generated in 0.0011 seconds