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An analysis of the utilisation of research information, in policy making and guidelines for the use of magnesium sulphate in the treatment of eclampsia and pre-eclampsia in South Africa

Background: The literature suggests that although the idea of using evidence to inform policy making has come into favour, actualising this idea in practice is complex. Within the framework of these debates this dissertation focuses on the uptake of findings from research into policy making for the use of magnesium sulphate in the treatment of eclampsia and pre-eclampsia within South Africa. Despite the publication over the past decade of evidence suggesting the effectiveness of magnesium sulphate as a treatment for eclampsia and pre-eclampsia, eclampsia remains a leading cause of maternal death in South Africa and in many other low and middle-income countries. This dissertation forms part of a larger study investigating the uptake of research into policy making in South Africa, Mozambique and Zimbabwe. Aim: To describe and analyse the actual and perceived utilisation of research information in policy making and guideline development for the use of magnesium sulphate in the treatment of eclampsia and pre-eclampsia. Methods: This qualitative study triangulated three techniques in order to understand research utilisation in contemporary policy making. The techniques employed were: policy document review, a historical overview and individual qualitative interviews with 15 key informants. Data generated through these methods are reflected upon in relation to each other and within the context of relevant scientific and intellectual debates. Findings: This study shows a positive example of research utilisation in policy making and guideline development. In the late 1990's in South Africa, prompted by factors such as the recent political change, policies and management guidelines were being developed for maternal health. Simultaneously evidence from randomized controlled trials and systematic reviews showed the effectiveness of magnesium sulphate for the treatment of eclampsia and pre-eclampsia. Policies developed during this period make explicit reference to the use of the most recent published evidence. The uptake of this evidence into national policy development is likely explained by the complex interaction of a range of factors: the existence of a previously established evidence-based culture among obstetricians; the movement of "networked" individuals immersed in that culture into key positions in the new government; the involvement of researchers in policy development; and the willingness of individuals and groups to lobby and advocate both for the development of policy and for the use of evidence in that policy. Discussion and Conclusions: The findings highlight the role played by researchers in developing evidence based policies and guidelines. It also points to the complexity of the relationship between knowledge production and the utilisation of research in policy. It suggests that while researchers may not be in control of factors such as political change, they are presented with windows of opportunity that may allow them to affect policy change. Their capacity to affect such change can be enhanced through collective action when researchers are organised through academic networks.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/26769
Date January 2006
CreatorsDaniels, Karen Lorraine
ContributorsLewin, Simon, Hoffmann, Margaret
PublisherUniversity of Cape Town, Faculty of Health Sciences, Department of Public Health and Family Medicine
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MPH
Formatapplication/pdf

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