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Signalling of E3 ubiquitin-protein ligases in the regulation of priming and tolerance of T cells

While these data therefore show that these molecules cannot be used as markers for T cell anergy, and while the search for a bona fide T cell anergy marker continues, it also opens up new possibilities for their role(s) in modulation of T cell activation. By advancing knowledge of the key signalling events that take place during antigen recognition, more targeted approaches for enhancing or inhibiting immunity or tolerance can be devised.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:525795
Date January 2010
CreatorsBicheiro, Luis Manuel Fernandes
PublisherUniversity of Glasgow
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Sourcehttp://theses.gla.ac.uk/2296/

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