The focus of this thesis was to investigate, especially in the context of obesity, the interactions among sleep duration and quality, and adverse health outcomes. Three comprehensive studies are described in the thesis: 1. A cross-sectional epidemiological study examined factors that are associated with both short and long sleep duration among an older Chinese population, and also assessed whether there was a link between sleep duration and chronic conditions such as obesity, hypertension, and diabetes. This study showed that long sleep duration was associated with increased risk for obesity among women. Additionally, demographic, socio-economic, and medical conditions were associated with sleep duration. Identifying potential factors that affect sleep will inform future interventions for improving sleep with potential downstream effect on obesity and other chronic disorders. 2. A cross-sectional study of patients with extreme obesity indicated that the prevalence of sleep disturbance is high in this patient population. There was a positive association between sleep disturbance factors and depressive symptoms and quality of life among these individuals. The findings emphasise the importance of adequate assessment and treatment of sleep problems in this patient population. 3. A systematic review and meta-analysis assessed the effectiveness of lifestyle modification interventions on the treatment of obstructive sleep apnoea (OSA). Lifestyle interventions such as dietary and physical activity improved OSA parameters, but were insufficient to normalise them. The findings will inform the development of future interventions for OSA, and are likely to contribute to clinical guidelines for OSA management.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:633338 |
| Date | January 2014 |
| Creators | Hosseini Araghi, Marzieh |
| Publisher | University of Birmingham |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://etheses.bham.ac.uk//id/eprint/5425/ |
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