An investigation into the pH stability of the BCNAs was also carried out and the parent analogue bearing a pentyphenyl side chain was found to be stable at a range of pHs. Finally, with the X-ray crystal structure of VZV thymidine kinase published we began a preliminary investigation into the possible interaction the BCNAs with this enzyme using molecular modelling
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:583557 |
| Date | January 2005 |
| Creators | Angell, Annette |
| Publisher | Cardiff University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://orca.cf.ac.uk/55384/ |
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