In summary, these observations demonstrate that lung function appears to be impaired by mucus secretion in an experimental animal model of chronic allergic asthma. The guinea pig model of chronic asthma may be utilised to investigate the development of a mucus hypersecretory phenotype in asthma or identify potential targets for the development of novel therapies aimed at reducing goblet cell mucus production or secretion.
Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:584512 |
Date | January 2009 |
Creators | John, Elinor |
Publisher | Cardiff University |
Source Sets | Ethos UK |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
Source | http://orca.cf.ac.uk/54093/ |
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