Antonín Hanuš 5. prosince 2014 This work deals with randomized clinical trials of medicaments. It examines three models of dependece of final values on initial values in case, that all variables are measured with some measurement error. For each model is derived effect of treatment estimate and its asymptotical properties, specifically consistency and asymptotical variance. The work mostly deals with linear model of analysis of covariance ANCOVA. The work fruther contents comparison of properties of estimates from all three models in case, that examined data come from a linear model. There is a comparison of asymptotical variances of estimates from all three models and for each of them there are examined conditions, when this model gives the best results. In the end there is a simulation study, which verifies all previous results. 1
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:336695 |
| Date | January 2015 |
| Creators | Hanuš, Antonín |
| Contributors | Kulich, Michal, Malý, Marek |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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