The GABAergic system in adult sensory cortex is affected by sensory deprivation, but little is known about how this predominant inhibitory system is affected during ontogeny. The present study investigates developmental effects of whisker trimming on GABAa receptors in rat barrel cortex. Rats trimmed for 6 wk beginning at birth and adulthood showed similar decreases in [3H]muscimol binding in deprived relative to non-deprived barrels, suggesting absence of a critical period.
Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc279232 |
Date | 08 1900 |
Creators | Salazar, Eduardo, 1962- |
Contributors | Fuchs, Jannon Lou, 1946-, Schwark, Harris, Tam, David C. |
Publisher | University of North Texas |
Source Sets | University of North Texas |
Language | English |
Detected Language | English |
Type | Thesis or Dissertation |
Format | iv, 23 leaves: ill., Text |
Rights | Public, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved., Salazar, Eduardo, 1962- |
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