The experiments reported in the present thesis investigated the effects of lesions to the anterior nuclei of the thalamus (ATN) on the acquisition of two spatial, working memory tasks performed on the eight-arm radial maze. In the task used in Experiment 1 and 2, the animals were required to discriminate and remember all the eight arms of the maze simultaneously. Lesions of the ATN produced impairments in the acquisition of this task, but the degree of impairment depended on the amount of damage within this region. In the task used in Experiment 3, the animals were required to discriminate and remember only two arms at once. Lesions of the ATN were shown to impair its acquisition even though performance was facilitated by the addition of visual intra-arms cues. These experiments suggest that the ATN may be involved in spatial learning and in the retention of non-specific information over time.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.22602 |
| Date | January 1995 |
| Creators | Leri, Francesco |
| Contributors | Petrides, Michael (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Arts (Department of Psychology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001467546, proquestno: MM05401, Theses scanned by UMI/ProQuest. |
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