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The immunobiology of the rat testicular macrophage / by Stephan Kern.

Includes bibliographical references (leaves 169-205). / xvii, 205, [33] leaves, [10] leaves of plates : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Suggests that the testicular macrophage exhibits characteristics similar to that of a suppressor macrophage phenotype. The inhibition of lymphocyte proliferation by the testicular macrophage, its unique cytokine profile, high basal production of GM-CSF and prostaglandins, and the refractoriness to LPS all suggests a role that contributes to the immune privilege that is afforded the testis. However, these aspects of testicular macrophage immuno-biology also support a role in local cell-cell communication and regulation of the normal physiology of the testis, and macrophages may be directly involved in Leydig cell steriogenesis. / Thesis (Ph.D.)--University of Adelaide, Dept. of Animal Science, 1997?

Identiferoai:union.ndltd.org:ADTP/263566
Date January 1995
CreatorsKern, Stephan, 1968-
Source SetsAustraliasian Digital Theses Program
Languageen_US
Detected LanguageEnglish

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