The aging population and increase of ambulatory surgeries have greatly increased strain on surgical and post-surgical staff that decreases the safety of care. Our overall goal is to find ways to decrease the time of anesthetic recovery to allow for more efficient post-surgical treatment. The specific aims of this study were to assess the correlations between neurocognitive recovery measures of attention and vigilance to brain dynamics. We analyzed reaction time via auditory psychomotor vigilance testing (aPVT) testing and the Richmond agitation-sedation scale (RASS) scores in 145 patients prior to and preceding surgery. Intraoperative electroencephalogram was also recorded for 115 of those patients. Data was analyzed to associate aPVT performance to recovery time and intraoperative brain dynamics. We found an association coefficient between reaction time and RASS recovery of 0.022 (p-value = 0.0001) showing a significant association. Further, we found age to be a significant confounding variable (p=0.04421) and included this in our association model. Lastly, there was no significant association found between intraoperative burst suppression and reaction time values (p=0.497). Overall, aPVT was found to be a robust test to assess recovery timeline in peri-operative anesthesia care unit patients. These results highlighted the potential use of an objective metric to track neurocognitive recovery after anesthesia, especially in elderly patients undergoing surgery.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/48236 |
| Date | 26 February 2024 |
| Creators | Hagood, Mackenzie Christie |
| Contributors | McKnight, C. James |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
| Rights | Attribution-NoDerivatives 4.0 International, http://creativecommons.org/licenses/by-nd/4.0/ |
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