Botulinum A toxin (BTX) has become increasingly recognized as a treatment option in the management of spasticity in children with cerebral palsy (CP). Preliminary evidence suggests that certain baseline characteristics of the child may affect responsiveness to BTX. However, the contribution of these factors has not been fully elucidated. / The primary objective of the study was to examine whether specific intrinsic and extrinsic characteristics of the child were associated with responsiveness to BTX. The results indicate that age, number of treatments, parenting stress and child's motivation were associated with the degree of change in gait pattern, level of ambulation, gross motor function and functional independence. The findings suggest that the contribution of contextual factors (personal and environmental) on responsiveness to BTX is underappreciated in children with mild CP. Identification of potential factors contributing to responsiveness to BTX will assist clinicians in identifying children who would benefit most from this procedure.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.98524 |
| Date | January 2005 |
| Creators | Yap, Rita. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (School of Physical and Occupational Therapy.) |
| Rights | © Rita Yap, 2005 |
| Relation | alephsysno: 002330994, proquestno: AAIMR24832, Theses scanned by UMI/ProQuest. |
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