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Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin

From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing,
both in human and veterinary medicine. Although initially designed to the treatment of Grampositive
microorganisms, this antimicrobial family has also been used to treat specific Gram-negative
bacteria. Some of them, as azithromycin, are considered in the armamentarium against
Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or
develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics
to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms
of macrolide resistance, currently described in Enterobacteriaceae.

Identiferoai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/620710
Date27 October 2016
CreatorsGomes, Cláudia, Martínez Puchol, Sandra, Palma, Noemí, Horna, Gertrudis, Ruiz-Roldán, Lidia, Pons, Maria J, Ruiz, Joaquim
Contributorsjoruiz.trabajo@gmail.com
PublisherTaylor & Francis
Source SetsUniversidad Peruana de Ciencias Aplicadas (UPC)
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/article
SourceUniversidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC
Rightsinfo:eu-repo/semantics/openAccess
Relationhttps://www.tandfonline.com/doi/full/10.3109/1040841X.2015.1136261

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