Background: COVID-19 is an ongoing pandemic. As of 11 May 2020, there are 4 013 728confirmed cases and 278 993 deaths. Smoking has been named as one possible factor regardingillness progression and severity. Aim: The aim of this systematic literature review is to examine if smokers are more at riskconsidering disease severity. Methods: This is a systematic literature study using the PubMed database. Inclusion andexclusion criteria were specified by using the PICOS format. Free text words and MeSH wordswere combined to create a search plan. The search was conducted twice, 26 April 2020 and 12May 2020. Full text articles were examined for eligibility by using inclusion and exclusioncriteria. An estimation of bias was conducted by using the MINORS criteria. Result: A total of seven articles were included. Of those, 5 reported a statistically significantrelationship between smoking and disease progression or death. Of these, 4 articles foundstatistical significance when correcting for confounders (hypertension, COPD, ischemic heartdisease, cardiac insufficiency). Conclusions: The result of this systematic literature review suggests that smoking enhancesthe severity of COVID-19. Due to the limited number of patients combined with a narrowgeographic area being studied, more research is needed to further evaluate and establish therelationship between smoking and COVID-19.
| Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:oru-85913 |
| Date | January 2020 |
| Creators | Lund, Maja |
| Publisher | Örebro universitet, Institutionen för medicinska vetenskaper |
| Source Sets | DiVA Archive at Upsalla University |
| Language | English |
| Detected Language | English |
| Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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