Vliv vakcinace slinami klíštěte \kur{Ixodes ricinus} na přenos \kur{Borrelia burgdorferi} a cytokinový profil hostitele / The influence of vaccination with saliva of the tick \kur{Ixodes ricinus} on the transmission of \kur{Borrelia burgdorferi} and cytokine profile of the host

Description

The tick Ixodes ricinus is one of the most important vectors of human pathogens like the spirochete Borrelia burgdorferi and TBE virus. The effect of repeated infestations with pathogen-free I. ricinus nymphs and the effect of vaccination with ticks saliva of the tick I. ricinus on the transmision Borrelia burgdorferi and on the production of the cytokines were studied. The draining lymph nodes of C3H/HeN mice were examined for IL-2, IFN-? and IL-10 production by antigen capture enzyme-linked immunosorbent assay. Spirochete load in skin, heart and bladder was examined by real-time polymerase chain reaction.

Links & Downloads

1. http://www.nusl.cz/ntk/nusl-53882

Tags

Additional Fields

Identifer	oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:53882
Date	January 2011
Creators	GREGOROVÁ, Eva
Source Sets	Czech ETDs
Language	Czech
Detected Language	English
Type	info:eu-repo/semantics/masterThesis
Rights	info:eu-repo/semantics/restrictedAccess