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Akustická stimulácia pomalovlnného spánku a jej vplyv na konsolidáciu pamäti u ľudí trpiacich nespavosťou / Acoustic stimulation of Slow wave sleep and its influence on consolidation of declarative memory in insomnia

Slow-wave sleep plays an important role in consolidation of declarative memory. From electrophysiological point of view, this process is dependent on a common occurrence and mutual integration of neocortical slow oscillations (< 1 Hz), hippocampal sharp-wave ripples (150-250 Hz) and thalamo-cortical sleep spindles (10-15 Hz). Previous studies demonstrated that periodic acoustic stimulation by pink noise pulses applied at frequency of sleep slow oscillation during slow wave sleep leads to prolongation of slow wave sleep and to enhancement in declarative memory performance in normal sleepers. Our study investigated this kind of periodic acoustic stimulation in its relation to sleep architecture and declarative memory of people suffering from insomnia due to which there often comes to a reduction in slow wave sleep which positively correlates with worsening of declarative memory performance. Our aim was to investigate if this kind of comparatively non-invasive brain stimulation has a potential to increase a total length of slow wave sleep and enhance declarative memory performance in insomnia. Our study revealed acoustic stimulation neither improved declarative memory performance nor it increased total length of slow-wave sleep. No positive association was found between level of declarative memory...

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:404974
Date January 2019
CreatorsOrendáčová, Mária
ContributorsKopřivová, Jana, Kelemen, Eduard
Source SetsCzech ETDs
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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