Sequence alignment is a basic but powerful technique in molecular biology.
Macromolecular sequences (DNA, RNA and protein sequences) can be aligned based
on some criteria. The goal of sequence alignment is to find the similarity and the
difference of input sequences. With various purposes, there are different algorithms
In this thesis, we present a new algorithm which aligns sequences with consideration of secondary structures. Traditionally, a sequence alignment algorithm
considers only the primary structure, which is the amino acid chain. When we make
use of the information of protein secondary structure such as alpha helix, beta sheet etc,
the sensitivity of pairwise alignment can be improved.
Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0821103-204917 |
Date | 21 August 2003 |
Creators | Cheng, Rei-Sing |
Contributors | Chin-Lung Lu, Zin-Huang Liu, Chang-Biau Yang, Yue-Li Wang, Yow-Lin Shine |
Publisher | NSYSU |
Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
Language | English |
Detected Language | English |
Type | text |
Format | application/pdf |
Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0821103-204917 |
Rights | off_campus_withheld, Copyright information available at source archive |
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