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Estrogen receptor involvement in the response of human keratinocytes to ultraviolet B irradiation

The signaling mechanisms involved in UVB-induced skin cancer are complex and although the scope of this work is inherently limited in focus, the findings may provide insight into how estrogen receptor signaling impacts cell growth, senescence, and apoptosis to protect keratinocytes. Additional signaling due to E2-activation of the estrogen receptor may provide back-up or redundant pathways in response to UVB.

Identiferoai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/6241
Date January 2014
CreatorsFarrington, Daphne L.
ContributorsSpandau, Dan F., Harrington, Maureen A., Nakshatri, Harikrishna
Source SetsIndiana University-Purdue University Indianapolis
Languageen_US
Detected LanguageEnglish
TypeThesis

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