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Differential Association of Vitronectin and Fibronectin with Glass and Electrospun Fibers of a Poly (D-Lysine) /Poly (Acrylic Acid)

Proteins represent major constituent of the extracellular matrix which plays an important role in the formation, maintenance and remodeling of tissues, this project focuses on adsorption of two specific serum proteins fibronectin (FN) and vitronectin (VTN) responsible for mediating cell matrix interaction through integrin binding, tripeptide Arg-Gly-Asp (RGD) sequence found in these protein features are recognized by αβV3 integrin which ultimately helps in clot formation.

Identiferoai:union.ndltd.org:USF/oai:scholarcommons.usf.edu:etd-7640
Date01 July 2016
CreatorsZafar, Syed Muhammad Sohaib Zafar
PublisherScholar Commons
Source SetsUniversity of South Flordia
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceGraduate Theses and Dissertations
Rightsdefault

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