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A study of the molecular and biological characteristics of ovine interleukin-12

Bibliography: leaves 172-214. Interleukin-12 (IL-12) is a heterodimeric cytokine composed of two disulphide-linked subunits, p35 and p40, which form biologically active p70. IL-12 is able to induce IFN-y production from T and NK cells, and promote the proliferation of mitogen-activated T cells. It is thought that IL-12 may be an important cytokine in the initiation and progression of allograft destruction. This thesis describes the characterisation of ovine IL-12.

Identiferoai:union.ndltd.org:ADTP/100088
Date January 2000
CreatorsSwinburne, Sarah Jane.
Source SetsAustraliasian Digital Theses Program
LanguageEnglish
Detected LanguageEnglish
RelationSUA

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