Selective synthesis of Neu5Ac2en and its oxazoline derivative using BF3.Et2O

Description

No / Application of the Lewis acid BF3·Et2O to the selective synthesis of 5-acetamido-2,6-anhydro-3,5-dideoxy-d-glycero-d-galacto-non-2-enonic acid (Neu5Ac2en) and the related oxazoline, methyl 7,8,9-tri-O-acetyl-2,3,4,5-tetradeoxy-2,3-didehydro-2,3-trideoxy-4',5'-dihydro-2'-methyloxazolo[5,4-d]- d-glycero-d-talo-non-2-enonate is described.

Links & Downloads

1. Ribeiro Morais G, Oliveira RS and Falconer RA (2009) Selective synthesis of Neu5Ac2en and its oxazoline derivative using BF3.Et2O. Tetrahedron Letters. 50(14): 1642-1644.
2. http://hdl.handle.net/10454/4616
3. https://doi.org/10.1016/j.tetlet.2009.01.117

Tags

Neu5Ac2en

; Lewis acid

; Sialic acid

; Glycal

; Oxazoline

; REF 2014

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/4616
Date	22 January 2009
Creators	Ribeiro Morais, Goreti, Oliveira, Rudi S., Falconer, Robert A.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text available in the repository