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Previous issue date: 2008-12-22 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / The number of equines that present some degree of inflammation of the lungs
is high, although exists physically healthy animals that present some degree of
airways inflammatory processes, in which precocious diagnosis would be only
possible through more detailed exams. The aims of this work are: evaluate
which exams could be related to the endoscopic classification of physically
healthy animals; verify the relationship with the age; research levels of the
parameters that can indicate tendencies of its increase or decrease and suggest
an appropriated number of individuals. The samples were divided in 4
Categories of Analyses: evaluation of the effectiveness of the technique, groups
of larger inclusion, groups of smaller inclusion and evaluation of the
relationships between the percentiles inside of the Categories 2 and 3. The
horses were accomplished through the following laboratorial exams: cytological,
hematological, Pro Coagulant Activity (PCA), Tumor Necrosis Factor (TNF) and
Nitric Oxid (NO). The results revealed that: in relation to the analyses of PCA,
only tests ex-life are appropriate. TNF suggests that the tests AD Lps and TT
Lps must be used. NO didn't generate any conclusions. The results revealed
that the following parameters could be used for future researches and
diagnosis: recovered volume, number of cells / mL, percentile of linfocytes, cloud
macrophages, giant macrophages, eosinophils, mastocytes, WBC, total
plasmatic proteins, PCA ex-life TT, TNF AD Lps and TT Lps. The number of
animals adapted for future experiments is of about 120, or 2 groups of 60
individuals. Finally, it is concluded that the dates observed in this present
research are valid for the diagnosis of inflammations in the equines lungs . / O n?mero de casos de equinos que apresentam algum grau de inflama??o do
aparelho respirat?rio ? extremamente alto, embora existam animais fisicamente
h?gidos mas que podem apresentar algum grau de processo inflamat?rio de
vias a?reas, cujo diagn?stico precoce s? seria poss?vel atrav?s de exames
mais precisos. Os objetivos da presente pesquisa s?o: avaliar quais exames
poderiam estar relacionados ? classifica??o endosc?pica de animais
fisicamente h?gidos; verificar a rela??o com a idade; pesquisar n?veis dos
par?metros avaliados que possam indicar tend?ncias de seu aumento ou
diminui??o e sugerir um n?mero m?nimo apropriado de animais. As amostras
foram divididas em 4 Categorias de An?lises: avalia??o da efic?cia da t?cnica,
grupos de abrang?ncia maior, grupos de abrang?ncia menor e avalia??o das
rela??es percentuais dentro das Categorias 2 e 3. Foram realizados os
seguintes exames laboratoriais: citol?gico, hematol?gico, Atividade pro
coagulante (APC), Fator de Necrose Tumoral (TNF) e ?xido N?trico (NO). Os
resultados revelaram que: em rela??o ?s an?lises de APC, somente testes exvivo
s?o apropriados. Para o TNF, sugere-se que os testes AD Lps e TT Lps
sejam utilizados. O NO, n?o gerou conclus?es. A pesquisa demonstrou ainda
que os seguintes par?metros poderiam ser utilizados para pesquisas futuras e
apoio diagn?stico: volume recuperado, n?mero de c?lulas por microlitro,
percentuais de linf?citos, macr?fagos espumosos, macr?fagos em sinc?cios,
eosin?filos, mast?citos, leucometria global, prote?nas plasm?ticas totais, APC
ex-vivo TT, TNF AD Lps e TT Lps. O n?mero de animais apropriados para
experimentos futuros ? de cerca de 120, ou 2 grupos de 60 indiv?duos. Concluise
que os dados observados na presente pesquisa s?o v?lidos para o aux?lio
diagn?stico de inflama??es no aparelho respirat?rio de equinos.
| Identifer | oai:union.ndltd.org:IBICT/oai:localhost:tede/846 |
| Date | 22 December 2008 |
| Creators | Viana, Eduardo Borges |
| Contributors | Botelho, Gilberto Garcia |
| Publisher | Universidade Federal Rural do Rio de Janeiro, Curso de P?s-Gradua??o em Ci?ncias Veterin?rias, UFRRJ, Brasil, Parasitologia Veterin?ria |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFRRJ, instname:Universidade Federal Rural do Rio de Janeiro, instacron:UFRRJ |
| Rights | info:eu-repo/semantics/openAccess |
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