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Hipertoninio hidroksietilkrakmolo tirpalo įtaka hemodinamikai, kvėpavimui ir homeostazei koreguojant hipovolemiją ligoniams po širdies operacijų / The effect of hypertonic Hydroxyethyl starch solution On haemodynamics, respiration And homeostasis in correction Of hypovolemia in patients After heart surgery

Conclusions 1. In comparison to the Ringer‘s acetate solution the use of HyperHaes® solution after coronary artery bypass surgery had positive effect on haemodynamic parameters: cardiac index increased (p<0.05), systolic volume index increased (p<0.05), cardiac afterload decreased, that is pulmonary vascular resistance index decreased (p<0.05) and systemic vascular resistance index decreased (p<0.05); the difference between the central and peripheral temperatures in experimental group (p<0.05). 2. The oxygen transport was more effective (oxygen delivery index increased (p<0.05)) when HyperHaes® solution was used in comparison to Ringer‘s acetate solution. 3. No substantial effect of HyperHaes® solution on the duration of artificial lung ventilation and intrapulmonary shunt size was defined. 4. The use of HyperHaes® solution influenced substantially some parameters of homeostasis (serum sodium concentration increased (p<0.05), serum potassium concentration decreased (p<0.05)) in compa-rison to Ringer‘s acetate solution. 5. Higher diuresis (p<0.01), lower need for the infusion therapy for the first 24 hours (p<0.05), lower total fluid balance (p<0.01) were determined in HyperHaes® group versus Ringer‘s acetate group. 6. No adverse effects (disturbances of homeostasis, neurologic symptoms, increased bleeding through mediastinal tubes, anaphylactic reactions) were noted in patients who received HyperHaes® solution.

Identiferoai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2005~D_20050923_130237-24808
Date23 September 2005
CreatorsŠneider, Edvin
ContributorsSkurvydas, Albertas, Kėvelaitis, Egidijus, Vaškelytė, Jolanta Justina, Vosylius, Saulius, Urbonavicius, Sigitas, Bolys, Ramūnas, Ivaškevičius, Juozas, Kaunas University of Medicine
PublisherLithuanian Academic Libraries Network (LABT), Kaunas University of Medicine
Source SetsLithuanian ETD submission system
LanguageLithuanian
Detected LanguageEnglish
TypeDoctoral thesis
Formatapplication/pdf
Sourcehttp://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20050923_130237-24808
RightsUnrestricted

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