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Small-molecule probes to explore cancer

Small molecules play important roles in therapeutics and drug discovery. Significant progress has been made by the chemical biology community to discover small-molecule probes to explore biological processes and to treat disease. This thesis describes both the discovery of novel probes for the Hedgehog (Hh) pathway and the application of small molecules in identifying cancer dependencies. / Chemistry and Chemical Biology

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12274182
Date04 June 2015
CreatorsSchaefer, Giannina Ines
ContributorsSchreiber, Stuart L.
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsopen

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