Staphylococcal tenosynovitis and osteomyelitis are world-wide problems of
broilers and broiler breeders caused by staphylococci. Pathogenesis of the disease is
ill defined. Avian heterophils are analogous to mammalian neutrophils but the
granules appear to be different.
The first chemotactic study was done on heterophils from chickens having
natural staphylococcal infection brought from a commercial broiler flock and on the
heterophils obtained from healthy 6-8 weeks old chickens brought from a local
hatchery as one day old chicks. In the second study, a chemotactic study was done
with three different staphylococci on heterophils obtained from healthy 6-8 weeks
old chickens brought from a local hatchery as one day old chicks.
Results for the first study showed a decreased chemotactic response in the
heterophils of chickens naturally infected with staphylococcus compared to healthy
chicken heterophils in response to minimum essential medium, pooled normal
chicken serum and E. coli endotoxin with normal chicken serum used as
chemoattractants. Second study results showed that pathogenic capsule type 5 and
type 8 Staphylococcus aureus isolates both induced chemotaxis in heterophils from
healthy chickens to a significantly greater degree than did a non-pathogenic
Staphylococcus xylosus. The Staphylococcus aureus isolate with capsule type 5
induced heterophil chemotaxis more than the capsule type 8 isolate. / Graduation date: 1993
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/35926 |
| Date | 30 September 1992 |
| Creators | Anwer, Mohammad |
| Contributors | Andreasen, James R. Jr |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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