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The impact of structure dimensions on initial bacterial adhesion

Substrate topography can have profound effects on initial bacterial adhesion during biofilm formation. We applied Staphylococcus epidermidis and Escherichia coli cells onto periodically structured substrates with different structure dimensions, structure types and wetting properties. We found a strong dependence of cell retention on the structure dimensions of the applied substrates. Periodicities in the range of the cell size increased, whereas smaller periodicities decreased cell retention, independent of contact time (minutes to hours) and hydrophobicity. These novel insights on the role of surface topography on bacterial retention might facilitate the development of non-fouling surfaces in the future.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:35958
Date07 January 2020
CreatorsHelbig, Ralf, Günther, Denise, Friedrichs, Jens, Rößler, Florian, Lasagni, Andrés, Werner, Carsten
PublisherRoyal Society of Chemistry
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation2047-4849, 10.1039/c6bm00078a

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