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Antibody-mediated rejection of arterialised venous allografts is inhibited by immunosuppression in rats

We determined in a rat model (1) the presence and dynamics of alloantibodies recognizing MHC complexes on quiescent Brown-Norway (BN) splenic cells in the sera of Lewis (LEW) recipients of Brown-Norway iliolumbar vein grafts under tacrolimus immunosuppression; and (2) the presence of immunoglobulins in the wall of acute rejected vein allografts.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa.de:bsz:15-qucosa-137757
Date14 March 2014
CreatorsSplith, Katrin, Jonas, Sven
ContributorsUniversität Leipzig, Translational Centre for Regenerative Medicine, Public Library of Science,
PublisherUniversitätsbibliothek Leipzig
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typedoc-type:article
Formatapplication/pdf
SourcePloS ONE March 2014 | Volume 9 | Issue 3 doi: 10.1371/journal.pone.0091212

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