yes / There are various techniques to enhance tissue regeneration
via the application of growth factors to the site of regeneration to
induce cells to proliferate, differentiate and regenerate. Generally,
direct application of growth factors has little effect [1] because
the growth factor diffuses out from the site of regeneration very
quickly. This is a problem that can be solved by a controlled
release of growth factor at the site of action over a long period
of time by use of a bioabsorbable scaffold. Growth factors are
protein based molecules in the body which are produced by cells
and attach to the cell surface. Growth factors bind to membrane
receptors, which in turn activate an intracellular signalling
pathway. This will activate or inhibit a gene causing either an
up regulation or down regulation of a gene product, which then
alters the cells behaviour.
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/11142 |
| Date | January 2014 |
| Creators | Sefat, Farshid |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Published version |
| Rights | © 2014 The Author. Open access, published by MedCrave Group Publishing. This work is licensed under a Creative Commons Attribution Licence. |
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