No / TCDD-inducible poly-ADP-ribose polymerase (TIPARP; also known as PARP7 and ARTD14) is a
mono-ADP-
ribosyltransferase
that has emerged as an important regulator of innate immunity, stem cell
pluripotency, and transcription factor regulation. Characterizing TIPARP’s catalytic activity and identifying
its target proteins are critical to understanding its cellular function. Here we describe methods that
we use to characterize TIPARP catalytic activity and its mono-ADP-ribosylation of its target proteins.
Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/18336 |
Date | 11 August 2018 |
Creators | Hutin, D., Grimaldi, Giulia, Matthews, J. |
Source Sets | Bradford Scholars |
Language | English |
Detected Language | English |
Type | Book chapter, No full-text in the repository |
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