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Modely pro přežití s možností vyléčení / Cure-rate models

In this work we deal with survival models, when we consider that with positive probability some patients never relapse because they are cured. We focus on two-component mixture model and model with biological motivation. For each model, we derive estimate of probability of cure and estimate of survival function of time to relaps of uncured patients by maximum likelihood method. Further we consider, that both probability of cure and survival time can depend on regressors. Models are then compared through simulation study. 1

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:345241
Date January 2016
CreatorsDrabinová, Adéla
ContributorsKulich, Michal, Omelka, Marek
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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