Prostate cancer is one of the leading causes of death by cancer for men. Focal therapy is being tested to target only the dominant cancer lesion in the prostate. However, due to the need to ensure that the laser is targeting only the cancer, a real-time treatment monitoring system is required. A combined optical-ultrasound monitoring system is in development at Princess Margaret Hospital based on different optical properties for coagulated versus normal tissue. In this project, we developed a light delivery and collection device that is compatible for use with an existing trans-rectal ultrasound-imaging probe. Computer-aided design software was used to visualize the prototype in relation to the trans-rectal ultrasound probe. This thesis describes the critical tasks necessary to assemble the final prototype, including listing of specifications, selection of device material based on safety and mechanical properties, method of prototype fabrication, positioning and fixation of optical fibers and testing.
| Identifer | oai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/42660 |
| Date | 20 November 2013 |
| Creators | Alam, Adeel |
| Contributors | Weersink, Robert, Wilson, Brian Campbell |
| Source Sets | University of Toronto |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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