La Tuberculosis Multidrogorresistente es un problema de salud pública que afecta al país. El consumo de alcohol se asocia frecuentemente a fracaso o abandono pero existen pocas investigaciones entre consumo de alcohol y TBMDR.
El presente estudio tuvo por objetivo determinar si el consumo excesivo de alcohol es un factor de riesgo de tuberculosis multidrogorresistente secundaria.
Metodología: Se realizó un estudio caso – control, denominando caso al paciente con TBMDR secundaria según criterios. Los controles fueron pacientes con TB no MDR que acudían a los mismos establecimientos en el mismo periodo que los casos. Se seleccionaron mínimamente 2 controles por caso. En total se reclutaron 44 casos y 125 controles, la muestra calculada fue de 43 casos y 86 controles.
Resultados: El consumo excesivo de alcohol fue detectado con la prueba de screening AUDIT (Alcohol Use Disorders Identification Test). Existe asociación entre consumo excesivo de alcohol y TBMDR (p=0,018). El 54,55% de los casos presenta consumo excesivo, mientras que solo el 34,40% de los controles presenta el mismo tipo de consumo. El consumo perjudicial de alcohol está asociado a TBMDR (p=0,02), el consumo de riesgo y la dependencia no estuvieron asociados a TBMDR. Existen diferencias estadísticamente significativas entre las medias del puntaje del AUDIT entre casos y controles (p=0,01). La variable abandono al tratamiento no es variable confusora. La probabilidad de TBMDR incrementa si el paciente presenta consumo excesivo de alcohol y además abandona el tratamiento de 0,35 a 0,99.
Conclusiones: El consumo excesivo de alcohol es un factor asociado a TBMDR secundaria, al igual que el consumo perjudicial. EL consumo de riesgo y la dependencia no estuvieron asociados a TB-MDR secundaria. / -- Background: Multidrug-Resistant Tuberculosis is a problem of public health goes affect country. The alcohol consumption is frequently associated to failure or abandonment but exist a few investigations between alcohol consumption and TBMDR. The present study had by objective to determine if the excessive alcohol consumption is a risk factor of secondary multidrogorresistente tuberculosis.
Methods: A case – control study was development, denominating case to the patient with secondary TBMDR according to criteria. The controls were patient with TB non MDR that went to the same health services in the same period that the cases. 2 controls by case were selected. Altogether 44 cases were recruited and 125 controls, the calculated sample was of 43 cases and 86 controls. The excessive alcohol consumption was detected with the test of screening AUDIT (Alcohol Use Disorders Identification Test).
Results: There was association between excessive alcohol consumption and TBMDR (p=0,018), 54.55% of the cases had excessive consumption, while 34.40% of the controls only had the same type of consumption. The detrimental alcohol consumption is associate to TBMDR (p=0,02), the risk consumption and the dependency was not associate to TBMDR. There was statistically significant differences between the averages of AUDIT between cases and controls (p=0,01). The variable abandonment of treatment is not confusor variable. TBMDR probability increases if the patient had excessive alcohol consumption and in addition leaves the treatment from 0.35 to 0,99.
Conclusion: Excessive consumption of alcohol and harmful consumptions are factors associated to secondary TBMDR. Risk consumption and dependence were not associated with secondary MDRTB.
| Identifer | oai:union.ndltd.org:Cybertesis/oai:cybertesis.unmsm.edu.pe:cybertesis/2524 |
| Date | January 2009 |
| Creators | Musayón Oblitas, Flor Yesenia |
| Contributors | Sanabria Rojas, Hernán Arturo |
| Publisher | Universidad Nacional Mayor de San Marcos |
| Source Sets | Universidad Nacional Mayor de San Marcos - SISBIB PERU |
| Language | Spanish |
| Detected Language | English |
| Type | info:eu-repo/semantics/bacherlorThesis |
| Source | Universidad Nacional Mayor de San Marcos, Repositorio de Tesis - UNMSM |
| Rights | info:eu-repo/semantics/openAccess |
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