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Assessment of CD44 and K19 as markers for circulating breast cancer cells using immunobead RT-PCR / by Michael Campbell Eaton.

Includes bibliographies. / [xvii], 173, [38] leaves, [18] leaves of plates : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / This thesis presents the development of an assay for reverse transcription-polymerase chain reaction (RT-PCR) to be applied to the immunomagnetic isolation of carcinoma cells, as a possible means of detecting small numbers of breast cancer cells in a haemopoietic environment. The messenger RNA expression of two different genes, CD44 and the cytokeratin K19, is assessed for suitability as tumour markers for the Immunobead RT-PCR method, and clinical results using K19 are presented. / Thesis (M.D.)--University of Adelaide, Dept. of Medicine, 1977?

Identiferoai:union.ndltd.org:ADTP/264011
Date January 1997
CreatorsEaton, Michael Campbell
Source SetsAustraliasian Digital Theses Program
Languageen_US
Detected LanguageEnglish

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