Charakterisierung und Weiterentwicklung eines Balanced Lethal Systems in \({Salmonella}\) \({spp}\) / Characterization and further development of a balanced lethal system in \({salmonella}\) \({spp}\)

Description

Charakterisierung und Weiterentwicklung eines Systems zur antibiotikafreien Plasmidstabilisierung und Sekretion heterologer Antigene über das Hämolysin a-Sekretionssystem in attenuiereten Salmonella-Stämmen. Ziel ist die Entwicklung tumorspezifischer Vakzine. / Characterization and further development of a system for antibiotic-free plasmid stabilization in attenuated salmonella strains and secretion-enabling of heterologous antigens via the hemolysin a-secretion system. Goal is the development of tumor-specific vaccines.

Links & Downloads

1. https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/7109
2. urn:nbn:de:bvb:20-opus-71092
3. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-71092
4. https://opus.bibliothek.uni-wuerzburg.de/files/7109/blssalmonella.pdf

Tags

Salmonella

Balanced lethal Systeme

Stabilisierung von Plasmiden

Tumorvaccine

Immuntherapie

ddc:610

Additional Fields

Identifer	oai:union.ndltd.org:uni-wuerzburg.de/oai:opus.bibliothek.uni-wuerzburg.de:7109
Date	January 2011
Creators	Rechtenwald, Christian
Source Sets	University of Würzburg
Language	deu
Detected Language	English
Type	doctoralthesis, doc-type:doctoralThesis
Format	application/pdf
Rights	https://opus.bibliothek.uni-wuerzburg.de/doku/lic_ohne_pod.php, info:eu-repo/semantics/openAccess