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Continuous multi-step synthesis by extrusion - telescoping solvent-free reactions for greater efficiency

Yes / Chemical manufacturing typically requires more than one step,
involving multiple batch processes, which makes synthesis at scale
laborious and wasteful. Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be
carried out as a continuous multi-component reaction (MCR), by
twin screw extrusion (TSE), in the complete absence of solvent. / EPSRC (EP/L019655/1).

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17693
Date13 February 2020
CreatorsCrawford, Deborah E., Miskimmin, C.K., Cahir, J., James, S.L.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Accepted manuscript
Rights© The Royal Society of Chemistry 2017. This work is made available online in accordance with the publisher's policies. Please refer to any applicable terms of use of the publisher., Unspecified

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