Can one classify biochemical pathways based on their topology? What is the topology of a biochemical pathway? What are the fundamental principles underlying different biochemical pathways involved in similar functional areas? Will one be able to characterize pathway "motifs" similar to motifs in proteins - i.e. reoccurring patterns in pathways? This thesis describes an attempt to develop a quantitative framework for the general representation and comparison of biochemical pathways. This quantitative framework involves a mathematical model to represent biochemical pathways and a set of similarity criteria to compare these biochemical pathways. We anticipate that such a tool would allow biologists to answer important questions such as the ones mentioned above.
| Identifer | oai:union.ndltd.org:uvic.ca/oai:dspace.library.uvic.ca:1828/2200 |
| Date | 16 February 2010 |
| Creators | Leung, Samuel |
| Contributors | Kapron, Bruce |
| Source Sets | University of Victoria |
| Language | English, English |
| Detected Language | English |
| Type | Thesis |
| Rights | Available to the World Wide Web |
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