Rhipicephalus microplus transmit two important diseases of livestock in South Africa,
namely Babesiosis and Anaplasmosis. As cattle still play a key role in the livelihood of
rural communities in the Eastern Cape province, animal health is of utmost importance
to maintain and strengthen these communities. In most rural areas of the Eastern Cape,
the South African government provides free dipping of cattle with amitraz.
Deltamethrin, a synthetic pyrethroid (SP), has been used as pour-on dip in a few
locations where there are no functional dips. Of concern, is the growing number of
global reports on the increase of acaricide resistance. Routine screening for resistance
to acaricides is therefore needed. In this study we investigated allele frequencies of
acaricide resistance-associated single nucleotide polymorphisms (SNPs) in R. microplus
ticks from the Engcobo Local Municipality. The estimated frequencies of amitraz
resistance-associated SNPs were 0.58 (at locus 1) and 0.32 (at locus 3). Resistance
against formamidines (amitraz) appears to be on the rise. The published mutation in the
voltage gated sodium channel (VGS) receptor gene (domain II segment 4-5 region),
known to confer resistance to synthetic pyrethroids, was not found. This could be
attributed to the low selection pressure against pyrethroids in the study area. / Dissertation (MSc)--University of Pretoria, 2018. / Veterinary Tropical Diseases / MSc / Unrestricted
Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:up/oai:repository.up.ac.za:2263/70546 |
Date | January 2018 |
Creators | Zanga, Jaison |
Contributors | Crafford, Jan Ernst, u16391196@tuks.co.za, Maritz-Olivier, Christine |
Publisher | University of Pretoria |
Source Sets | South African National ETD Portal |
Language | English |
Detected Language | English |
Type | Dissertation |
Rights | © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
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