ABBREVIATIONS
A – amniocentesis
DA – deceleration angle
FMH – fetomaternal haemorrhage
MCA – middle cerebral artery
MoM – multiples of median
PI – pulsatility index
PSV – peak systolic velocity
RI – resistance index
SA – splenic artery
SGA – small for gestational age
HDN – haemolytic disease of newborn
1. INTRODUCTION
Rhesus alloimmunization occurs when a rhesus negative woman has an immunologic response to a paternally derived red-cell antigen that is foreign to the mother and inherited by the fetus. Rhesus alloimmunization and haemolytic disease of the newborn continues to occur as a serious complication of pregnancy despite well-organized antenatal antiD prophylaxis programs. At the Perinatal Center of Kaunas University
of Medicine the incidence has remained stable at around 60 cases of alloimmunized pregnancies and from 30 to 40 cases of haemolytic disease of newborn annually. Perinatal mortality in cases of rhesus alloimmunization has been estimated to be at around 1 to 3.5 percent. Due to failure to apply or comply with antiD prophylaxis guidelines and limitations of the prophylaxis rhesus sensitization continues to occur.
Rhesus alloimmunization is diagnosed when the test of a rhesus negative woman for red cell alloantibodies is positive. Prognosis for the fetus and perinatal outcomes depends much on how severely the fetus is affected by the disease at the time of diagnosis. The main pathological entity of the disease is fetal red blood cell destruction and... [to full text]
| Identifer | oai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2005~D_20060202_153259-36891 |
| Date | 02 February 2006 |
| Creators | Mačiulevičienė, Regina |
| Contributors | Skurvydas, Albertas, Jurkevičius, Renaldas, Švedas, Eimantas, Sladkevičius, Povilas, Nadišauskienė, Rūta Jolanta, Maleckienė, Laima, Kaunas University of Medicine |
| Publisher | Lithuanian Academic Libraries Network (LABT), Kaunas University of Medicine |
| Source Sets | Lithuanian ETD submission system |
| Language | Lithuanian |
| Detected Language | English |
| Type | Doctoral thesis |
| Format | application/pdf |
| Source | http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20060202_153259-36891 |
| Rights | Unrestricted |
Page generated in 0.0026 seconds