Soft biological tissues, being live and due to their physiological structures,
display considerably complex mechanical behaviors. For a better understanding
and use in various applications, first study to be carried out is the tests made
particularly as in vivo. An indenter test device developed for this purpose in the
METU, Department of Mechanical Engineering, Biomechanics Laboratory is
operational.
In this study, in order to carry out precise and dependable tests, initially, various
tests and improvements were conducted on the device and the software
controlling the device. At the end of this study, displacement and load
measurement accuracies and precisions were improved. Better algorithms for
filtering the noisy data were prepared. Some test protocols within the software
were improved and new protocols were annexed. To be able to conduct more
dependable tests a new connection system was attached to the device. In order to
study the anisotropic behavior of soft tissues ellipsoid tips were designed and
produced.
In the second phase of the study, tests on medial forearm were carried out. In
these tests, hysteresis, relaxation and creep behaviors displaying the viscoelastic
v
properties of the soft biological tissues were observed. In addition to viscoelastic
behaviors, preconditioning (Mullin& / #8217 / s) effect and anisotropic response were
examined. By using the results of the relaxation and creep tests, parameters of
the Prony series capable of modelling these data were determined.
With this study, some important conclusions regarding the soft biological tissues
were drawn and thus the behaviors of the soft biological tissues were better
understood. Besides, the difficulties inherent to in-vivo tests were recognized
and actions to reduce these difficulties were explained. Finally, clean
experimental data, to be used in the computer simulations, were obtained.
| Identifer | oai:union.ndltd.org:METU/oai:etd.lib.metu.edu.tr:http://etd.lib.metu.edu.tr/upload/12610071/index.pdf |
| Date | 01 September 2008 |
| Creators | Petekkaya, Ali Tolga |
| Contributors | Tonuk, Ergin |
| Publisher | METU |
| Source Sets | Middle East Technical Univ. |
| Language | English |
| Detected Language | English |
| Type | M.S. Thesis |
| Format | text/pdf |
| Rights | To liberate the content for public access |
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