A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10รข day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation existed between lens weight and total ATP content in control lenses <r=O.509, n=153), but this relationship disappeared with selenite treatment <r=0.023, n=153). There was a significant inhibition by selenite on lens growth from 4 through 11 days after an injection. / Master of Science
| Identifer | oai:union.ndltd.org:VTETD/oai:vtechworks.lib.vt.edu:10919/45655 |
| Date | 14 November 2012 |
| Creators | Adamchak, Marsha Ann |
| Contributors | Biochemistry and Nutrition, Hess, John L., Bunce, George Edwin, Gregory, Eugene M. |
| Publisher | Virginia Tech |
| Source Sets | Virginia Tech Theses and Dissertation |
| Language | English |
| Detected Language | English |
| Type | Thesis, Text |
| Format | vii, 84 leaves, BTD, application/pdf, application/pdf |
| Rights | In Copyright, http://rightsstatements.org/vocab/InC/1.0/ |
| Relation | OCLC# 15183254, LD5655.V855_1986.A342.pdf |
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