This report extends findings (Duffy & Mitchell, 2013) of a dramatic recovery of
vision in the deprived eye of amblyopic kittens following a short ‘dark-pulse’ (a 10 day
period of darkness) to situations of clinical relevance. To this end, the initial deprivation
began at post-natal day 7 rather than post-natal day 30. As before, the dark-pulse was
imposed either immediately after the initial monocular deprivation, or was delayed
several weeks after stable amblyopia was establsihed. In some animals, this dark-pulse
was shortened, or disrupted by short periods of daily binocular visual experience. The
effects on the visual acuity and alignment acuity of the two eyes were documented as
well as the effects on binocular depth perception. The benefits of a short dark-pulse were
identical to those of the prior study. A dark-pulse of 5 days was ineffective as was a
dark-pulse interrupted daily by light for 30-minutes.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:NSHD.ca#10222/21665 |
| Date | 23 January 2013 |
| Creators | MacNeill, Katelyn |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
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