PURPOSE: To compare white matter neuron density across 3 regions, prefrontal, temporal, and posterior parietal (PFC, TE, PP) in macaque monkey, with further analysis of subdivisions within the gyral white matter.
METHODS: Histological tissue from three adult macaque monkeys, previously prepared with the neuron-specific pan-neuronal marker Neuronal-N, was used for analysis. Tissue was digitized and processed electronically to investigate cross- and intra-regional differences in the distribution of white matter neurons.
RESULTS: Statistical analysis showed significant differences across all regions sampled and across most intra-regional subdivisions, although the more conservative post-hoc tests failed to find significant differences between specific regions.
CONCLUSIONS: The results of the current study support regional differences. Further studies using a larger sample size may help elucidate the relatively unknown properties of white matter neurons.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/19204 |
| Date | 03 November 2016 |
| Creators | Lee, Daniel |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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