Purpose:
Assess for an association of wait times to melanoma treatment with overall survival.
Methods:
Retrospective review of Ontario patients with melanoma, with descriptive and survival analyses.
Results:
Median wait times were 43 days (interquartile range (IQR), 24-64) for wide local excision (WLE), 59 days (IQR, 41-81) for sentinel lymph node biopsy (SNB), 63 days (IQR, 43-91) for lymph node dissection (LND), 124 days (IQR, 96-150) for medical therapy, and 130 days (IQR, 89.5-157.5) for radiation therapy. In multivariate analysis, wait times to treatment were not associated with overall survival for WLE (hazard ratio (HR), 0.97; 95% confidence interval (CI), 0.87-1.08; p=0.62), SNB (HR, 0.89; 95% CI, 0.74-1.07; p=0.21), LND (HR, 0.99; 95% CI, 0.89-1.11; p=0.92), medical therapy (HR, 0.94; 95% CI, 0.80-1.10; p=0.41) or radiation therapy (HR, 0.80; 95% CI, 0.61-1.03; p=0.08).
Conclusion:
Overall survival for patients with melanoma was not associated with wait times to surgical, medical or radiation therapy.
| Identifer | oai:union.ndltd.org:uottawa.ca/oai:ruor.uottawa.ca:10393/33365 |
| Date | January 2015 |
| Creators | Crawford, Alyson |
| Contributors | Van Walraven, Carl |
| Publisher | Université d'Ottawa / University of Ottawa |
| Source Sets | Université d’Ottawa |
| Language | English |
| Detected Language | English |
| Type | Thesis |
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