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Development of an applicationfor individualized Warfarin treatment : Independent Project in Engineering Physics

A problem with the widley usedanticoagulant medicine Warfarin hasalways been that the therapeutic dosevaries from person to person and thatthere has not been any methods toestimate individually-based dosingregimens. By using a new populationmodeldescribing the relationship betweenWarfarin dose and INR(internationalnormalized ratio) response fordifferent individuals based on their age,weight and genotypes, a user friendly,dose estimating program has beendeveloped in Java. The applicationestimates the INR given the individualparameters and dosing, but it's alsopossible to estimate the predicted dosegiven the desired INR. The applicationmakes it possible for others to take partof the model, and to give a moreindividualized Warfarin treatment inclinical practice.

Identiferoai:union.ndltd.org:UPSALLA1/oai:DiVA.org:uu-180358
Date January 2012
CreatorsHellman, Jacob, Dahlberg, Jonny
PublisherUppsala universitet, Institutionen för teknikvetenskaper, Uppsala universitet, Institutionen för teknikvetenskaper
Source SetsDiVA Archive at Upsalla University
LanguageEnglish
Detected LanguageEnglish
TypeStudent thesis, info:eu-repo/semantics/bachelorThesis, text
Formatapplication/pdf
Rightsinfo:eu-repo/semantics/openAccess
RelationTVE ; 12 049 augusti

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