Flukes of the genus Trichobilharzia are typical parasites using aquatic gastropods as intermediate hosts and birds as definitive hosts. However, infectious stages in open water are able to penetrate the skin of a mammal, including humans, and thereby induce a hypersensitivity reaction known as swimmer's itch. Infection with neurotropic species T. regenti in ducks induces an increase in level of IgY antibody which recognize certain parasitic antigens. In this work, these parameters in two other relative but visceral species, T. szidati and T. franki, and cross-reactivity of antibodies in serum of infected duck against heterologous parasitic antigen by ELISA and Western blot were characterized. Antibodies of ducks infected with T. szidati showed very low reactivity with all three parasitic antigens in compare to ducks infected with T. franki or T. regenti. The previously identified strongly immunogenic T. regenti antigens have been evaluated as species non-specific for all trichobilharzia species studied, but useful for avian fluke infection in wild individuals diagnosis.
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:395047 |
| Date | January 2019 |
| Creators | HAVELKOVÁ, Markéta |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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