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Effect on eating behavior, lipids, lipoproteins and lipid peroxidation of a high monounsaturated diet in postmenopausal women with type 2 diabetes

The objective of this study was to compare the effects on eating behavior,
lipids, lipoproteins, lipid peroxidation, and glycemic control in women with type 2
diabetes of a high-monounsaturated fat diet (HM) compared to a high-carbohydrate
diet (HC).
In an outpatient feeding study, ten hypertriglyceridemic postmenopausal type
2 diabetic women alternately for six weeks consumed the HM and HC diets. On the
HM diet, 45% of total calories were consumed as carbohydrate and 40% as fat
(27% monounsaturated) compared to 55% carbohydrate and 30% fat (10%
monounsaturated) in the HC diet. At the beginning and end of each diet phase, total
lipids, lipoproteins, lipid peroxidation, and glycemic variables were measured. For 8
days in each diet phase eating pattern frequency, palatability of foods, hunger and
fullness were assessed. At the end of each diet phase, taste testing to determine
preference for fat was conducted.
Total cholesterol was significantly decreased on the HC diet. Serum
triglyceride, very low density lipoprotein (VLDL) triglyceride and cholesterol, and
apolipoproteins A-1 and B were not significantly different on the two diets. When
comparing initial to final values, both diets lowered LDL-C; however, the change
was greater on the HM diet. Lipid peroxidation variables improved when the HM
diet was consumed. Glycemic variables improved on both diets.
No significant differences between total number of eating episodes on the
HM and HC diet phases were found. Both diets were rated as highly palatable.
Hunger and fullness ratings varied within and between subjects. However, fullness
was more commonly experienced than hunger on both HM and the HC diet.
Preference for fat was not found at the end ofHM or HC diets. However, subjects
differed significantly in ratings for liking of foods that were salty, sour, and bitter
when compared to nondiabetic women.
Consumption of the HM and HC diets did not result in deterioration of lipid
status. The HM diet by virtue of less oxidation of the LDL particle and
improvement of glycemic control provides an important advantage over the HC diet.
A description of eating behavior of women with type 2 diabetes emerged. / Graduation date: 2000

Identiferoai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/27662
Date23 August 1999
CreatorsDavidson, Sue B.
ContributorsWander, Rosemary C.
Source SetsOregon State University
Languageen_US
Detected LanguageEnglish
TypeThesis/Dissertation

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