Abstract
The influence of the X and Y chromosomes on the size and shape
of the dental arches and occlusion as well as on craniofacial cephalometric
dimensions, angles and dimensional ratios is studied. The material
consists of Finnish patients with sex chromosome aneuploidies and
normal population controls from the "Kvantti Study" series,
which was collected in the 1970's and 1980's at
the Institute of Dentistry, University of Turku. The patients are
five individuals with complete testicular feminization (CTF), eight
47,XYY males, and fourteen 45,X/46,XX females. The controls
are population female and male controls, as well as five first degree
relatives of the individuals with CTF, three of the 47,XYY males
and nine of the 45,X/46,XX females studied. Dental arch
dimensions and occlusion as well as craniofacial cephalometric dimensions,
angles and dimensional ratios are measured from dental study casts
and standardized lateral cephalograms.
The results show that the presence of the Y chromosome in
46,XY females and the supernumerary Y chromosomal gene(s) in 47,XYY
males result in the enlargement of the dental arches and craniofacial
dimensions without substantial effects on dimensional ratios and
plane angles, but with special influence on the growth of the mandibular
corpus. The reduction of X chromosomal genetic material in 45,X/46,XX
females results in the reduction of craniofacial dimensions, affecting dimensional
ratios and especially plane angles of the cranial base.
| Identifer | oai:union.ndltd.org:oulo.fi/oai:oulu.fi:isbn951-42-5374-4 |
| Date | 14 September 1999 |
| Creators | Grön, M. (Mathias) |
| Publisher | University of Oulu |
| Source Sets | University of Oulu |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/doctoralThesis, info:eu-repo/semantics/publishedVersion |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess, © University of Oulu, 1999 |
| Relation | info:eu-repo/semantics/altIdentifier/pissn/0355-3221, info:eu-repo/semantics/altIdentifier/eissn/1796-2234 |
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