The structure and function of brain show sexual dimorphism in vertebrates. Brain sexual differentiation is resulted from the neural development. The neural development of brain is determined by genetic regulation and also influenced by external environmental factors(ex: temperature¡B neurotransmitter ). Serotonin (5-hydroxytrptamine, 5-HT) function as a neurotransmitter and/or neuromodulator in the central nervous system. Serotonin plays a important role in the development of the central nervous system via serotonin receptor¡CAstrocyte has the role of neural supporting and neural protection in CNS. Astrocyte has the important role of brain development. In the present study, the influence of temperature on the proliferation of astrocyte was investigated.These results show that the proliferation of astrocyte are varied with the temperature. Serotonin is not involved in the proliferation of astrocyte .Wherease,but has an effect on the ratio 5-HT+-cell in the astrocyte culture via the 5-HT1A receptor.
| Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0806109-172038 |
| Date | 06 August 2009 |
| Creators | Lin, Che-ming |
| Contributors | I -Ming Jou, Ching-Lin Tsai, Li-Hsueh Wang |
| Publisher | NSYSU |
| Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
| Language | Cholon |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0806109-172038 |
| Rights | not_available, Copyright information available at source archive |
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